Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048429 | 0.90 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2SIGMAR1LTB4R2 | |
| SCHEMBL9427333 | 0.89 | PTGIR (0.58) | PTGIRTBXAS1PTGDR2SIGMAR1KDM4C | |
| SCHEMBL9048020 | 0.81 | PTGIR (0.67) | PTGIRTBXAS1PTGDR2SIGMAR1KDM4C | |
| SCHEMBL9427087 | 0.81 | PTGIR (0.81) | PTGIRTBXAS1PTGDR2SIGMAR1KDM4C | |
| SCHEMBL9047049 | 0.80 | PTGIR (0.62) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL8858400 | 0.79 | PTGIR (0.75) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL9050868 | 0.77 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2ALDH1A1KDM4C | |
| SCHEMBL8858404 | 0.77 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048090 | 0.77 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL8858393 | 0.76 | PTGIR (0.52) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |