Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.69 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047142 | 0.90 | PTGIR (0.60) | PTGIRTBXAS1LTB4R2PTGDR2SIGMAR1 | |
| SCHEMBL9048020 | 0.89 | PTGIR (0.67) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL8858400 | 0.87 | PTGIR (0.75) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL8858404 | 0.85 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9047049 | 0.84 | PTGIR (0.62) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL9048846 | 0.83 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL8858439 | 0.82 | PTGIR (0.68) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048090 | 0.82 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2SIGMAR1 | |
| SCHEMBL9048458 | 0.82 | PTGIR (0.45) | PTGIRLTB4R2SIGMAR1 | |
| SCHEMBL9048557 | 0.82 | PTGIR (1.00) | PTGIRTBXAS1PTGDR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |