⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19711770 | 0.74 | KMT2A (0.47) | — | |
| SCHEMBL22045856 | 0.74 | KMT2A (0.47) | — | |
| SCHEMBL19711769 | 0.73 | KMT2A (0.40) | — | |
| SCHEMBL4181392 | 0.72 | — | — | |
| SCHEMBL2021592 | 0.72 | — | — | |
| SCHEMBL10182573 | 0.72 | — | — | |
| SCHEMBL1705495 | 0.70 | CRBN (0.43) | — | |
| SCHEMBL22810866 | 0.70 | — | — | |
| SCHEMBL21300802 | 0.70 | — | — | |
| Hydrogen Sulfide SCHEMBL9272622 | 0.70 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326250-A1 | CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2017-11-16 | — | — | US | disclosed |
| EP-2217927-B1 | VISUAL GLUCOSE SENSOR AND METHODS OF USE THEREOF | BECTON DICKINSON CO (US) | 2013-10-09 | — | — | EP | disclosed |
| US-8129525-B2 | Long wavelength thiol-reactive fluorophores | BECTON DICKINSON AND COMPANY (US) | 2012-03-06 | — | — | US | disclosed |
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110184168-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100003763-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| WO-2009052299-A2 | VISUAL GLUCOSE SENSOR AND METHODS OF USE THEREOF | BECTON, DICKINSON AND COMPANY (US) | 2009-04-23 | — | — | WO | disclosed |