Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050661 | 0.81 | HTT (0.45) | ALDH1A1LMNAHTT | |
| SCHEMBL9049074 | 0.77 | AKT1 (0.54) | KITPDE10AHRH4HTTAKT1 | |
| SCHEMBL29243325 | 0.75 | KMT2A (0.46) | ALDH1A1LMNAPDE1BHTT | |
| SCHEMBL29243323 | 0.75 | KMT2A (0.46) | ALDH1A1LMNAPDE1BHTT | |
| SCHEMBL30068001 | 0.75 | KMT2A (0.46) | ALDH1A1LMNAPDE1BHTT | |
| SCHEMBL26647188 | 0.75 | KMT2A (0.46) | ALDH1A1LMNAPDE1BHTT | |
| SCHEMBL4351559 | 0.75 | KIT (0.46) | KITPDE10AHRH4MAPK13MAPK12 | |
| SCHEMBL26600945 | 0.75 | KIT (0.46) | KITPDE10AHRH4MAPK13MAPK12 | |
| SCHEMBL3882291 | 0.75 | MAPK13 (0.46) | KITHRH4MAPK13MAPK12MAPK11 | |
| SCHEMBL3884627 | 0.75 | MAPK13 (0.46) | KITHRH4MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714896-A1 | INDOL DERIVATIVES USEFUL FOR THE TREATMENT OF MIGRAINE, COMPOSITION AND UTILIZATION | VITA-INVEST, S.A. (ES) | 1996-06-05 | — | — | EP | disclosed |