Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SI | P14410 | 3/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047333 | 1.00 | MAPT (0.54) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL9048176 | 0.91 | MAPT (0.56) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL9048905 | 0.91 | MAPT (0.56) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL11790820 | 0.81 | MAPT (0.46) | MAPTHPGDALDH1A1HTTGAA | |
| SCHEMBL11790814 | 0.81 | MAPT (0.46) | MAPTHPGDALDH1A1HTTGAA | |
| SCHEMBL6868060 | 0.81 | HSP90AA1 (0.62) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL9046525 | 0.81 | MAPT (0.47) | MAPTHPGDCYP1A2ALDH1A1DDB1 | |
| SCHEMBL14527555 | 0.81 | HSP90AA1 (0.62) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL5171544 | 0.81 | HSP90AA1 (0.62) | MAPTHPGDCYP1A2F3ALDH1A1 | |
| SCHEMBL9047291 | 0.81 | MAPT (0.47) | MAPTHPGDCYP1A2F3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | claimed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |