Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048176 | 1.00 | MAPT (0.56) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9047330 | 0.91 | MAPT (0.54) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9047333 | 0.91 | MAPT (0.54) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9047291 | 0.90 | MAPT (0.47) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9047297 | 0.90 | MAPT (0.47) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9046529 | 0.90 | MAPT (0.47) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL9046525 | 0.90 | MAPT (0.47) | MAPTHPGDDDB1CRBNCYP1A2 | |
| SCHEMBL23265135 | 0.79 | MAOB (0.47) | MAPTHPGDDDB1CRBNCYP1A2 | |
| Hydrochloric Acid SCHEMBL1524474 | 0.79 | HSP90AA1 (0.76) | MAPTHPGDCYP1A2HSP90AA1MITF | |
| Hydrochloric Acid SCHEMBL9301717 | 0.79 | HSP90AA1 (0.76) | MAPTHPGDCYP1A2HSP90AA1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | claimed |
| EP-0378953-B1 | Benzylidene azolyl methyl cycloalkane and its use as a fungicide | RHONE POULENC AGROCHIMIE (FR) | 1996-06-05 | — | — | EP | disclosed |