SCHEMBL9047374

SCHEMBL9047374

CCOC(=O)CCC=CCC=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.59
PGR P06401 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
PTGS2 P35354 1/20 0.59
PDE4D Q08499 1/20 0.59
ALDH1A1 P00352 4/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CYP1A2 P05177 1/20 0.42
MGLL Q99685 1/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
MAPT P10636 3/20 0.41
FFAR1 O14842 1/20 0.41
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048386 1.00 NR1I2 (0.59) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL9183887 0.88 NR1I2 (0.60) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL9183882 0.88 NR1I2 (0.60) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL11399358 0.86 NR1I2 (0.51) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL11301330 0.86 NR1I2 (0.51) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL11399361 0.86 NR1I2 (0.51) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL15130626 0.85 ADORA3 (0.80) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL4425859 0.85 ADORA3 (0.80) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL4984694 0.85 ADORA3 (0.80) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL442556 0.85 ADORA3 (0.80) NR1I2PGRADORA3PTGS2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718273-A1 Ethyl 6-formyl-4-hexenoate MERRELL PHARMACEUTICALS INC. (US) 1996-06-26 EP disclosed
EP-0718273-A1 Ethyl 6-formyl-4-hexenoate MERRELL PHARMACEUTICALS INC. (US) 1996-06-26 EP disclosed