Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16046661 | 0.98 | HTR1A (0.74) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL30406834 | 0.95 | HTR1A (0.74) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL12774179 | 0.85 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL14355885 | 0.84 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL4673484 | 0.84 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL17659018 | 0.83 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL19381655 | 0.83 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19381661 | 0.83 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19381657 | 0.83 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL19381141 | 0.83 | MEN1 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734383-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1996-10-02 | — | — | EP | disclosed |