Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050549 | 0.92 | PTGIR (0.46) | PTGIRLMNAPTGDR2TBXAS1PPARD | |
| SCHEMBL9047526 | 0.91 | PTGIR (0.45) | PTGIRPTGDR2TBXAS1MEN1KMT2A | |
| SCHEMBL9048717 | 0.78 | PTGIR (0.50) | PTGIRLMNAPTGDR2TBXAS1PPARD | |
| SCHEMBL9047031 | 0.72 | PTGIR (0.48) | PTGIRLMNAPTGDR2TBXAS1 | |
| SCHEMBL9049275 | 0.71 | PTGIR (0.45) | PTGIRPTGDR2 | |
| SCHEMBL10357321 | 0.71 | CA1 (0.49) | PTGIRLMNAPTGDR2MEN1KMT2A | |
| SCHEMBL16977037 | 0.70 | PTGDR2 (0.55) | PTGIRLMNAPTGDR2TBXAS1 | |
| SCHEMBL10550905 | 0.70 | PTGIR (0.52) | PTGIRPTGDR2TBXAS1MEN1KMT2A | |
| SCHEMBL9045328 | 0.70 | PTGIR (0.64) | PTGIRLMNAPTGDR2TBXAS1MEN1 | |
| SCHEMBL1838402 | 0.69 | PTGIR (0.56) | PTGIRPTGDR2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |