Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049275 | 0.94 | PTGIR (0.45) | PTGIRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL9047031 | 0.90 | PTGIR (0.48) | PTGIRPTGDR2TBXAS1LMNALIPG | |
| SCHEMBL9049238 | 0.84 | PTGIR (0.43) | PTGIRPTGDR2POLBSMN1; SMN2 | |
| SCHEMBL9047440 | 0.78 | PTGIR (0.47) | PTGIRPTGDR2TBXAS1LMNAPPARD | |
| SCHEMBL9049212 | 0.78 | PTGIR (0.54) | PTGIR | |
| SCHEMBL9050549 | 0.77 | PTGIR (0.46) | PTGIRPTGDR2TBXAS1LMNATDP1 | |
| SCHEMBL9568035 | 0.77 | HTT (0.45) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9047526 | 0.76 | PTGIR (0.45) | PTGIRPTGDR2TBXAS1PPARD | |
| SCHEMBL9050877 | 0.74 | PTGIR (0.49) | PTGIRPTGDR2TBXAS1LIPG | |
| SCHEMBL16977037 | 0.74 | PTGDR2 (0.55) | PTGIRPTGDR2TBXAS1LMNALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |