SCHEMBL9047707

SCHEMBL9047707

CCCN(CCC1CCc2c(cccc2OC(=O)CO)C1)C(=O)CN(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 14/20 0.41
DRD2 P14416 3/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9050740 0.92 PTGIR (0.42) PTGIRDRD2DRD4DRD3
SCHEMBL9049474 0.89 PTGIR (0.43) PTGIR
SCHEMBL9047709 0.87 PTGIR (0.57) PTGIR
SCHEMBL9047459 0.83 PTGIR (0.44) PTGIR
SCHEMBL9047704 0.82 DRD2 (0.37) PTGIRDRD2DRD4DRD3
SCHEMBL9050742 0.79 PTGIR (0.58) PTGIR
SCHEMBL8858418 0.77 PTGIR (0.53) PTGIRDRD2
SCHEMBL9050300 0.76 PTGIR (0.50) PTGIR
SCHEMBL9049479 0.75 PTGIR (0.59) PTGIR
SCHEMBL9050737 0.74 NPSR1 (0.37) PTGIRDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP claimed