Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059222 | 0.90 | HTR1D (0.50) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9050530 | 0.83 | HTR1D (0.68) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9050506 | 0.83 | HTR1D (0.73) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9333416 | 0.81 | HTR1D (0.67) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL7724517 | 0.79 | HTR1D (0.77) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL29611473 | 0.79 | HTR1D (0.77) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9054954 | 0.79 | HTR1D (0.57) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL8985966 | 0.76 | HTR1D (0.71) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9054646 | 0.76 | HTR1D (0.63) | HTR1DSLC6A4HTR1BHTR2AMEN1 | |
| SCHEMBL29431890 | 0.75 | HTR1D (0.68) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724580-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011243-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |