⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4984276 | 0.96 | — | — | |
| SCHEMBL20913237 | 0.96 | — | — | |
| Magnesium SCHEMBL31472238 | 0.96 | — | — | |
| SCHEMBL29597118 | 0.87 | — | — | |
| SCHEMBL5712208 | 0.81 | TSHR (0.47) | — | |
| SCHEMBL28421175 | 0.79 | — | — | |
| SCHEMBL1553372 | 0.79 | — | — | |
| Water SCHEMBL11361709 | 0.76 | — | — | |
| Tetrahydrofuran SCHEMBL27896184 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL321725 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645971-B | Method for directly preparing alkyl borate compound from alkyl halide | 中国科学院兰州化学物理研究所 | 2021-12-24 | — | — | CN | claimed |
| CN-108727320-B | Method for catalytically synthesizing 4-chloro tetrahydropyrane compound by taking titanocene dichloride as Lewis acid and chloride ion source | 陕西师范大学 | 2021-06-01 | — | — | CN | claimed |
| US-3931236-A | Oxidation and dehydrohalogenation of halotetrahydropyrans | PHILLIPS PETROLEUM COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12540157-B2 | Oxysterols and methods of use thereof | Sage Therapeutics, LLC (US) | 2026-02-03 | — | — | US | disclosed |
| US-20250382300-A1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC (US) | 2025-12-18 | — | — | US | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-12466831-B2 | Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use | MERCK SHARP & DOHME LLC (US) | 2025-11-11 | — | — | US | disclosed |
| EP-3883575-B1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC (US) | 2025-10-08 | — | — | EP | disclosed |
| EP-4616908-A2 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2025-09-17 | — | — | EP | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| WO-1998047869-A1 | CARBOCYCLIC AND HETEROCYCLIC SUBSTITUTED SEMICARBAZONES AND THIOSEMICARBAZONES AND THE USE THEREOF | COCENSYS, INC. (US) | 1998-10-29 | — | — | WO | disclosed |
| EP-0741707-B1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE POULENC RORER LTD (GB) | 1998-04-01 | — | — | EP | disclosed |
| EP-0741707-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020578-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-08-03 | — | — | WO | disclosed |
| EP-0406839-B1 | Process for the preparation of 1-(4-tetrahydropyranyl) or 1-(4-tetrahydrothiopyranyl)-prop-1-en-3-ones | BASF AG (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5221753-A | PREPARATION OF 1-(4-TETRAHYDROPYRANYL)- OR 1-(4-TETRAHYDROTHIOPYRANYL)PROP-1-EN-3-ONES | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0406839-A2 | Process for the preparation of 1-(4-tetrahydropyranyl) or 1-(4-tetrahydrothiopyranyl)-prop-1-en-3-ones | BASF Aktiengesellschaft (DE) | 1991-01-09 | — | — | EP | disclosed |
| US-3931236-A | Oxidation and dehydrohalogenation of halotetrahydropyrans | PHILLIPS PETROLEUM COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931236-A | Oxidation and dehydrohalogenation of halotetrahydropyrans | PHILLIPS PETROLEUM COMPANY (US) | 1976-01-06 | — | — | US | disclosed |