Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047857 | 1.00 | HDAC1 (0.46) | HDAC1MAOBCCR3NPSR1MEN1 | |
| SCHEMBL9046652 | 0.90 | KMT2A (0.47) | HDAC1MAOBMEN1KMT2AMAPT | |
| SCHEMBL9046644 | 0.90 | KMT2A (0.47) | HDAC1MAOBMEN1KMT2AMAPT | |
| SCHEMBL9050261 | 0.84 | KDM4E (0.57) | HDAC1MAOBMEN1KMT2AMAPT | |
| SCHEMBL9050279 | 0.84 | KDM4E (0.57) | HDAC1MAOBMEN1KMT2AMAPT | |
| SCHEMBL31412042 | 0.76 | IGF1R (0.49) | HDAC1CCR3NPSR1MEN1KMT2A | |
| SCHEMBL29049372 | 0.76 | IGF1R (0.49) | HDAC1CCR3NPSR1MEN1KMT2A | |
| SCHEMBL3438411 | 0.75 | CCR3 (0.46) | HDAC1MAOBCCR3NPSR1MEN1 | |
| SCHEMBL3438408 | 0.75 | CCR3 (0.46) | HDAC1MAOBCCR3NPSR1MEN1 | |
| SCHEMBL9047611 | 0.75 | KDM4E (0.51) | HDAC1MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |