Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412042 | 1.00 | IGF1R (0.49) | IGF1RGSK3BGSK3AALDH1A1MEN1 | |
| SCHEMBL29049408 | 0.84 | NAT1 (0.58) | GSK3AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31412071 | 0.84 | NAT1 (0.58) | GSK3AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15421408 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL29049438 | 0.76 | TTR (0.58) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL31412119 | 0.76 | TTR (0.58) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL9047857 | 0.76 | HDAC1 (0.46) | IGF1RALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9047846 | 0.76 | HDAC1 (0.46) | IGF1RALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14181813 | 0.75 | MAPT (0.58) | IGF1RALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3438411 | 0.74 | CCR3 (0.46) | IGF1RALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554079-B | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |