Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680278 | 0.88 | CRHR1 (0.48) | CRHR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL9047025 | 0.84 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL9047531 | 0.79 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL9047577 | 0.79 | CRHR1 (0.49) | CRHR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL7680765 | 0.79 | CRHR1 (0.46) | CRHR1TSHRMAPK1L3MBTL1 | |
| SCHEMBL8033081 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL9045274 | 0.78 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL7687483 | 0.77 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL7684604 | 0.76 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL9045452 | 0.76 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |