Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644274 | 0.89 | MRGPRX4 (0.58) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL18973243 | 0.84 | MRGPRX4 (0.52) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL18255998 | 0.84 | MRGPRX4 (0.52) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10641694 | 0.82 | MRGPRX4 (0.51) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL8145313 | 0.82 | MRGPRX4 (0.51) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL5243287 | 0.82 | MRGPRX4 (0.51) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10644438 | 0.82 | MRGPRX4 (0.55) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL2220207 | 0.81 | MRGPRX4 (0.51) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL20020329 | 0.81 | MRGPRX4 (0.46) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL14198670 | 0.80 | MRGPRX4 (0.60) | MRGPRX4MAPK1HSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |