Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403456 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL11858671 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL9047413 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL9046105 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL9046957 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNATHRBMTORMDM2 | |
| Hydrochloric Acid SCHEMBL11852644 | 0.99 | L3MBTL1 (0.64) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL13003024 | 0.96 | L3MBTL1 (0.64) | L3MBTL1LMNATHRBMTORMDM2 | |
| Elacytarabine SCHEMBL15140172 | 0.95 | L3MBTL1 (0.59) | L3MBTL1LMNATHRBMTORMDM2 | |
| Elacytarabine SCHEMBL12137632 | 0.95 | L3MBTL1 (0.59) | L3MBTL1LMNATHRBMTORMDM2 | |
| SCHEMBL7684283 | 0.95 | L3MBTL1 (0.59) | L3MBTL1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | claimed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |