Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15198667 | 0.91 | DPP4 (0.49) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL904489 | 0.86 | DPP4 (0.51) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL15198666 | 0.83 | DPP4 (0.48) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL904499 | 0.81 | KCNH2 (0.45) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL904591 | 0.81 | DPP4 (0.46) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL904569 | 0.81 | DPP4 (0.50) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL15198665 | 0.80 | DPP4 (0.45) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL904588 | 0.80 | DPP4 (0.45) | DPP4DPP7KCNH2ALDH1A1GAA | |
| SCHEMBL15199819 | 0.78 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1PRSS1 | |
| SCHEMBL904597 | 0.77 | DPP4 (0.43) | DPP4DPP7KCNH2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621899-B1 | NOVEL METHYLCYCLOHEXANE DERIVATIVES AND USES THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-10-21 | — | — | EP | disclosed |
| WO-2012044046-A2 | NOVEL METHYLCYCLOHEXANE DERIVATIVES AND USES THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-04-05 | — | — | WO | disclosed |