Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048416 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAFAAHALOX15 | |
| SCHEMBL10979214 | 0.83 | TSHR (0.41) | ALDH1A1HSD17B10LMNAFAAHALOX15 | |
| SCHEMBL10979212 | 0.83 | TSHR (0.41) | ALDH1A1HSD17B10LMNAFAAHALOX15 | |
| SCHEMBL11045594 | 0.73 | TSHR (0.44) | ALDH1A1HSD17B10LMNAFAAHALOX15 | |
| SCHEMBL11045597 | 0.73 | TSHR (0.44) | ALDH1A1HSD17B10LMNAFAAHALOX15 | |
| SCHEMBL3240184 | 0.72 | — | — | |
| SCHEMBL2149292 | 0.72 | — | — | |
| SCHEMBL11650348 | 0.69 | TSHR (0.34) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL11650346 | 0.69 | TSHR (0.34) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9167626 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544588-B1 | Intermediates for the preparation of vitamin A and E and of carotenoids | RHONE POULENC NUTRITION ANIMAL (FR) | 1996-01-31 | — | — | EP | disclosed |
| US-5449844-A | Chemical condensation in the presence of acid catalyst | RHONE-POULENC NUTRITION ANIMALE (FR) | 1995-09-12 | — | — | US | disclosed |
| EP-0544588-A1 | Intermediates for the preparation of vitamin A and E and of carotenoids | RHONE-POULENC NUTRITION ANIMALE (FR) | 1993-06-02 | — | — | EP | disclosed |