Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.78 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | MTOR | P42345 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904849 | 0.81 | OPRM1 (0.57) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL904851 | 0.78 | OPRM1 (0.52) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL904838 | 0.78 | OPRM1 (0.53) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL904839 | 0.77 | DRD3 (0.54) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL18309848 | 0.77 | OPRM1 (0.57) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL13651197 | 0.77 | OPRL1 (0.87) | OPRL1OPRM1DRD3OPRK1DRD2 | |
| SCHEMBL904826 | 0.77 | HTR2A (0.58) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL3881201 | 0.76 | OPRM1 (0.56) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL904918 | 0.74 | OPRM1 (0.51) | OPRL1OPRM1HTR2AHTR2CADRA1A | |
| SCHEMBL905040 | 0.74 | OPRM1 (0.51) | OPRL1OPRM1HTR2AHTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |