Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 13/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 13/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401251 | 0.79 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL21401258 | 0.77 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL31578481 | 0.77 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL8478307 | 0.77 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL29368290 | 0.76 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL9255140 | 0.75 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL21401252 | 0.74 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2626829 | 0.74 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8480333 | 0.71 | TSHR (0.42) | ADRA2AADRA2CADRA1AKCNH2TP53 | |
| Hydrochloric Acid SCHEMBL8482510 | 0.71 | AOC3 (0.43) | ADRA2AADRA2BADRA2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589484-B1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO LTD (JP) | 1996-10-16 | — | — | EP | claimed |
| EP-0589484-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | claimed |
| EP-0383281-A1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-22 | — | — | EP | claimed |
| US-5472984-A | 1,2-ethanediol derivative and salt thereof and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |