Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.66 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047995 | 0.91 | PTGIR (0.58) | PTGIRTBXAS1SIGMAR1ALDH1A1HTT | |
| SCHEMBL9048216 | 0.88 | PTGIR (0.71) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL9048590 | 0.84 | PTGIR (0.71) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL8858477 | 0.83 | PTGIR (0.52) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048350 | 0.83 | PTGIR (0.69) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL9051699 | 0.83 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9049589 | 0.82 | PTGIR (0.68) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL9048575 | 0.81 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9045328 | 0.81 | PTGIR (0.64) | PTGIRTBXAS1SIGMAR1PTGDR2 | |
| SCHEMBL9046463 | 0.81 | PTGIR (0.62) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |