Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858415 | 0.87 | PTGIR (0.56) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9047995 | 0.85 | PTGIR (0.58) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9048529 | 0.83 | PTGIR (0.66) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL8858437 | 0.83 | PTGIR (0.56) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9046175 | 0.81 | PTGIR (0.60) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9049799 | 0.81 | F11 (0.42) | F11 | |
| SCHEMBL9048631 | 0.80 | PTGIR (0.54) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9568034 | 0.79 | PSMB5 (0.57) | F11 | |
| SCHEMBL8858726 | 0.78 | PTGIR (0.56) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9046416 | 0.77 | PTGIR (0.70) | PTGIRPTGDR2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |