Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050300 | 0.90 | PTGIR (0.50) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9047874 | 0.90 | PTGIR (0.45) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9049015 | 0.87 | PTGIR (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL8414288 | 0.86 | MTNR1A (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9045695 | 0.86 | MTNR1A (0.44) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9048564 | 0.84 | CHRM2 (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL8858427 | 0.83 | MTNR1A (0.41) | PTGIRCHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL7777377 | 0.80 | CYP19A1 (0.64) | CHRM2CHRM1CHRM3CYP19A1MTNR1A | |
| SCHEMBL8414260 | 0.80 | PTGIR (0.65) | PTGIR | |
| SCHEMBL9048138 | 0.80 | PTGIR (0.52) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |