SCHEMBL9048628

SCHEMBL9048628

CCCCCCC(=O)c1cc2ccccc2s1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.60
BCL2L1 Q07817 1/20 0.53
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC9 Q9UKV0 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
NPY2R P49146 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12123735 0.88 BCL2L1 (0.59) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL7384635 0.85 BCL2L1 (0.53) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL3380570 0.84 BCL2L1 (0.51) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL4308244 0.84 BCL2L1 (0.51) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL4526358 0.84 BCL2L1 (0.54) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL3383078 0.83 HDAC1 (0.68) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL13783956 0.83 HDAC1 (0.68) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL10472933 0.82 BCL2L1 (0.60) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL13310334 0.82 RAB9A (0.56) RAB9ABCL2L1HDAC3HDAC4HDAC1
SCHEMBL6384612 0.81 HDAC1 (0.66) RAB9ABCL2L1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0339599-B1 Process for producing acylaromatic compounds SUMITOMO CHEMICAL CO (JP) 1996-08-21 EP disclosed
EP-0339599-A2 Process for producing acylaromatic compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-02 EP disclosed