⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049710 | 1.00 | — | — | |
| SCHEMBL9048010 | 1.00 | — | — | |
| SCHEMBL9051453 | 1.00 | — | — | |
| SCHEMBL9050657 | 1.00 | — | — | |
| SCHEMBL9315931 | 0.85 | SOAT1 (0.55) | — | |
| SCHEMBL8962528 | 0.85 | — | — | |
| SCHEMBL9136172 | 0.83 | SMN1; SMN2 (0.64) | — | |
| SCHEMBL8962502 | 0.82 | SOAT1 (0.54) | — | |
| SCHEMBL10699124 | 0.81 | SOAT1 (0.69) | — | |
| SCHEMBL7568038 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559898-B1 | ANILIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5475130-A | A thio, sulfonyl, sulfoxidyl or sulfonate acetamide compound as enzyme inhibitor of acyl-coenzyme A cholesterol acyltransferase | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0559898-A1 | ANILIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-09-15 | — | — | EP | disclosed |