SCHEMBL9136172

SCHEMBL9136172

CC(C)c1cccc(C(C)C)c1NC(=O)CS(=O)(=O)CCCl

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.64
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SOAT2 O75908 1/20 0.47
SOAT1 P35610 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048720 0.83
SCHEMBL9051453 0.83
SCHEMBL9050657 0.83
SCHEMBL9048010 0.83
SCHEMBL9049710 0.83
SCHEMBL8041519 0.80 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2ATDP1SOAT2
SCHEMBL190379 0.79 SMN1; SMN2 (1.00) SMN1; SMN2MEN1KMT2ATDP1SOAT2
SCHEMBL8962535 0.78 SMN1; SMN2 (0.60) SMN1; SMN2MEN1KMT2ATDP1SOAT2
SCHEMBL9843936 0.77 SMN1; SMN2 (0.77) SMN1; SMN2MEN1KMT2ATDP1SOAT2
SCHEMBL8941392 0.75 SMN1; SMN2 (0.56) SMN1; SMN2MEN1KMT2ATDP1SOAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416212-A Antilipemic agents, enzyme inhibitors and anticholesterol agents TAISHO PHARMACEUTICAL CO., LTD. (JP) 1995-05-16 US disclosed
EP-0619312-A1 ANILIDE DERIVATIVE TAISHO PHARMACEUTICAL CO. LTD (JP) 1994-10-12 EP disclosed