Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810576 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CA2EPHX2 | |
| SCHEMBL8813947 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CA2EPHX2 | |
| SCHEMBL8812303 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CA2EPHX2 | |
| SCHEMBL8810614 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CA2EPHX2 | |
| SCHEMBL8811510 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CA2EPHX2 | |
| SCHEMBL8810622 | 0.88 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8813524 | 0.88 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8813121 | 0.88 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8812352 | 0.88 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8811135 | 0.88 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |