Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048134 | 0.86 | PTGIR (0.45) | PTGIR | |
| SCHEMBL9046598 | 0.84 | POLB (0.41) | PTGIR | |
| SCHEMBL9048858 | 0.83 | PTGIR (0.46) | PTGIRTBXAS1 | |
| SCHEMBL9046845 | 0.83 | HPGD (0.47) | PTGIRBCHE | |
| SCHEMBL9048750 | 0.81 | PTGIR (0.69) | PTGIRTBXAS1 | |
| SCHEMBL9048747 | 0.81 | PTGIR (0.51) | PTGIRPRMT5WDR77TBXAS1 | |
| SCHEMBL9048366 | 0.78 | PTGIR (0.43) | PTGIR | |
| SCHEMBL9045194 | 0.76 | CHRM2 (0.41) | PTGIRTBXAS1 | |
| SCHEMBL9049412 | 0.73 | ALDH1A1 (0.39) | PTGIR | |
| SCHEMBL9046465 | 0.73 | PRMT5 (0.41) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |