Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046353 | 0.94 | PTGIR (0.53) | PTGIRTBXAS1PTGDR2PTGDR | |
| SCHEMBL9427127 | 0.86 | PTGIR (0.43) | PTGIRTBXAS1 | |
| SCHEMBL9050354 | 0.85 | PTGIR (0.57) | PTGIRTBXAS1PTGDR2PTGDR | |
| SCHEMBL9046342 | 0.80 | PTGIR (0.38) | PTGIRTBXAS1 | |
| SCHEMBL9048479 | 0.79 | PTGIR (0.50) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048146 | 0.78 | PTGIR (0.60) | PTGIRPTGDR | |
| SCHEMBL9050054 | 0.78 | PTGIR (0.55) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9048942 | 0.78 | PTGIR (0.55) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9568023 | 0.78 | TRPM8 (0.48) | — | |
| SCHEMBL9048588 | 0.77 | PTGIR (0.54) | PTGIRTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |