Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20423531 | 0.71 | ADRA2A (0.34) | HTR2CADRA2AADRA2BDRD2 | |
| SCHEMBL9851225 | 0.68 | HTR2C (0.35) | HTR2CADRA2AADRA2BKDM4EMAPT | |
| Iodide SCHEMBL5402073 | 0.68 | NOTUM (0.44) | NOTUMKDM4EMAPT | |
| SCHEMBL29352476 | 0.67 | KDM4E (0.45) | HTR2CADRA2AADRA2BKDM4EMAPT | |
| SCHEMBL582334 | 0.65 | NOTUM (0.46) | NOTUMKDM4E | |
| SCHEMBL6989045 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL8013061 | 0.64 | NOTUM (0.44) | NOTUMKDM4E | |
| Bromide SCHEMBL5406141 | 0.64 | NOTUM (0.44) | NOTUMKDM4E | |
| Bromide SCHEMBL8014734 | 0.64 | NOTUM (0.44) | NOTUMKDM4E | |
| Hydrochloric Acid SCHEMBL5396075 | 0.64 | NOTUM (0.44) | NOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691973-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022871-A1 | THIENO-INDOLE DERIVATIVES AS 5HT2c AND 5HT2b ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-10-13 | — | — | WO | disclosed |