SCHEMBL9049016

SCHEMBL9049016

O=C(O)COc1cccc2c1CCC(CCCO)C2

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.67
PTGDR Q13258 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7778598 0.93 PTGIR (0.69) PTGIRPTGDR
SCHEMBL8414260 0.88 PTGIR (0.65) PTGIRPTGDR
SCHEMBL8858428 0.84 PTGIR (0.64) PTGIRPTGDR
SCHEMBL9049015 0.82 PTGIR (0.48) PTGIR
SCHEMBL8858465 0.81 PTGIR (0.64) PTGIRPTGDR
SCHEMBL8858411 0.81 PTGIR (0.48) PTGIRPTGDR
SCHEMBL9158515 0.80 PTGIR (0.66) PTGIRPTGDR
SCHEMBL8410514 0.80 PTGIR (0.54) PTGIRPTGDR
SCHEMBL9049012 0.80 CHRM2 (0.45) PTGIRPTGDR
SCHEMBL8858413 0.79 PTGIR (0.46) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP disclosed
US-5344836-A Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-09-06 US disclosed