Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858426 | 0.94 | PTGIR (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL8858411 | 0.87 | PTGIR (0.48) | PTGIRCHRM2CHRM1CHRM3PTGDR | |
| SCHEMBL8858419 | 0.80 | PTGIR (0.49) | PTGIRCHRM2CHRM1CHRM3PTGDR | |
| SCHEMBL9049015 | 0.80 | PTGIR (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9049016 | 0.79 | PTGIR (0.67) | PTGIRPTGDR | |
| SCHEMBL8858438 | 0.79 | MTNR1A (0.44) | PTGIRCHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL9049012 | 0.76 | CHRM2 (0.45) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL8410517 | 0.73 | PTGIR (0.48) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL9050300 | 0.72 | PTGIR (0.50) | PTGIRCHRM2CHRM1CHRM3CYP19A1 | |
| SCHEMBL8812824 | 0.72 | PTGIR (0.47) | PTGIRCHRM2CHRM1CHRM3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |