Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.54 |
| ▸ | HRH1 | P35367 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | MTOR | P42345 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904939 | 0.81 | HTR2A (0.57) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL904826 | 0.79 | HTR2A (0.58) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL904839 | 0.77 | DRD3 (0.54) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL904883 | 0.77 | HTR2A (0.52) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL11096272 | 0.75 | CHRM2 (0.54) | DRD3OPRK1OPRM1CYP3A4CYP2D6 | |
| SCHEMBL904847 | 0.75 | HTR2A (0.54) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL18309848 | 0.75 | OPRM1 (0.57) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL13504722 | 0.75 | HTR2A (0.59) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL904876 | 0.74 | HTR2A (0.51) | HTR2AADRA1AHRH1DRD3OPRD1 | |
| SCHEMBL3881201 | 0.74 | OPRM1 (0.56) | HTR2AADRA1AHRH1DRD3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |