Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 9/20 | 0.46 |
| ▸ | HTR1B | P28222 | 7/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460623 | 0.94 | OPRM1 (0.60) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| SCHEMBL5385661 | 0.81 | OPRM1 (0.64) | OPRM1OPRK1OPRL1HTR1DHTR1B | |
| Oxalic Acid SCHEMBL9046271 | 0.78 | OPRM1 (0.53) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9048518 | 0.78 | OPRM1 (0.58) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9049148 | 0.77 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Hydrochloric Acid SCHEMBL9048212 | 0.76 | OPRM1 (0.57) | OPRM1OPRK1OPRL1HTR6HTR1D | |
| SCHEMBL8876513 | 0.76 | OPRM1 (0.66) | OPRM1OPRK1OPRL1HTR1DHTR1B | |
| Oxalic Acid SCHEMBL9048940 | 0.76 | OPRM1 (0.51) | OPRM1OPRK1OPRL1HTR1DHTR1B | |
| Oxalic Acid SCHEMBL9048237 | 0.76 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9045773 | 0.76 | OPRM1 (0.51) | OPRM1OPRK1OPRL1HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |