Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
| ▸ | DRD3 | P35462 | 4/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045886 | 0.97 | PSMB5 (0.32) | GLSPSMB5PSMB8DRD2DRD3 | |
| SCHEMBL9170727 | 0.94 | PSMB5 (0.32) | PSMB5PSMB8DRD2DRD3DRD4 | |
| SCHEMBL9050214 | 0.88 | ESR1 (0.36) | GLSPSMB5PSMB8DRD2DRD3 | |
| SCHEMBL9051129 | 0.82 | PREP (0.41) | DRD2DRD3DRD1DRD4 | |
| SCHEMBL9048115 | 0.81 | PSMB8 (0.31) | GLSPSMB5PSMB8DRD2DRD3 | |
| SCHEMBL9046795 | 0.79 | PREP (0.42) | DRD2DRD3DRD1DRD4 | |
| SCHEMBL9050316 | 0.79 | FLT3 (0.39) | — | |
| SCHEMBL9049645 | 0.78 | PSMB8 (0.32) | PSMB5PSMB8DRD2DRD3DRD4 | |
| SCHEMBL9045213 | 0.77 | PREP (0.41) | DRD2DRD3DRD1DRD4 | |
| SCHEMBL9049751 | 0.76 | PREP (0.45) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |