Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | DRD3 | P35462 | 3/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049645 | 0.97 | PSMB8 (0.32) | PSMB8PSMB5PIN1DRD2DRD3 | |
| SCHEMBL9050156 | 0.94 | PREP (0.33) | PSMB8PSMB5PIN1DRD2DRD3 | |
| SCHEMBL9049668 | 0.89 | PSMB5 (0.35) | PSMB8PSMB5PIN1DRD2DRD3 | |
| SCHEMBL9049197 | 0.81 | GLS (0.32) | PSMB8PSMB5DRD2DRD3DRD4 | |
| SCHEMBL9046667 | 0.81 | RAB9A (0.36) | — | |
| SCHEMBL9045886 | 0.78 | PSMB5 (0.32) | PSMB8PSMB5DRD2DRD3DRD4 | |
| SCHEMBL9050872 | 0.78 | — | — | |
| SCHEMBL9046320 | 0.78 | PREP (0.47) | DRD2HTR2B | |
| SCHEMBL9049794 | 0.77 | GBA1 (0.31) | — | |
| SCHEMBL9050045 | 0.76 | PREP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |