Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 0.63 |
| ▸ | THRA | P10827 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048693 | 0.85 | PIM1 (0.49) | PIM1THRATHRBFLT3POLB | |
| SCHEMBL30419935 | 0.82 | PIM1 (0.64) | PIM1PIM2LMNATP53FLT3 | |
| SCHEMBL2897831 | 0.82 | PIM1 (0.64) | PIM1PIM2LMNATP53FLT3 | |
| SCHEMBL31287888 | 0.81 | THRA (0.60) | PIM1THRATHRBPIM2LMNA | |
| SCHEMBL335319 | 0.78 | KDM4E (0.66) | PIM1THRATHRBLMNATP53 | |
| SCHEMBL29527237 | 0.78 | KDM4E (0.66) | PIM1THRATHRBLMNATP53 | |
| SCHEMBL5221248 | 0.78 | PIM1 (1.00) | PIM1THRATHRBPIM2LMNA | |
| SCHEMBL30530818 | 0.78 | THRA (0.52) | PIM1THRATHRBFLT3POLB | |
| Hydrochloric Acid SCHEMBL11498190 | 0.77 | KDM4E (0.64) | PIM1THRATHRBLMNATP53 | |
| SCHEMBL11113704 | 0.77 | PIM1 (0.63) | PIM1THRATHRBPIM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |