Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 9/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051167 | 0.95 | PREP (0.42) | PREPDPP4RAB9AF2 | |
| SCHEMBL9047912 | 0.95 | PREP (0.42) | PREPDPP4RAB9AF2 | |
| SCHEMBL9049953 | 0.90 | PREP (0.36) | PREPF2ALDH1A1GAA | |
| SCHEMBL9050343 | 0.86 | PREP (0.44) | PREPDPP4 | |
| SCHEMBL9172981 | 0.86 | F2 (0.35) | PREPF2ALDH1A1 | |
| SCHEMBL9050262 | 0.86 | F2 (0.35) | PREPF2ALDH1A1 | |
| SCHEMBL9050728 | 0.85 | PREP (0.42) | PREPDPP4 | |
| SCHEMBL9048233 | 0.84 | PREP (0.46) | PREP | |
| SCHEMBL9175056 | 0.84 | PREP (0.42) | PREP | |
| SCHEMBL9167239 | 0.84 | PREP (0.42) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |