Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 7/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14705952 | 0.88 | ESR1 (0.56) | ESR1ESR2PARP1PKMTAAR1 | |
| SCHEMBL15946973 | 0.85 | ESR1 (0.54) | ESR1ESR2PKMTAAR1KDM4E | |
| SCHEMBL14278521 | 0.79 | ESR1 (0.69) | ESR1ESR2PARP1TAAR1KDM4E | |
| SCHEMBL9049053 | 0.78 | KDM4E (0.50) | ESR1ESR2KDM4EHPGDHSD17B10 | |
| SCHEMBL3116645 | 0.78 | PIN1 (0.56) | PARP1IKBKBCDC7CCNA2CDK2 | |
| SCHEMBL24427668 | 0.76 | KDM4E (0.54) | PARP1IKBKBCDC7CCNA2CDK2 | |
| SCHEMBL14705957 | 0.76 | ESR1 (0.47) | ESR1ESR2CDC7KDM4EHPGD | |
| SCHEMBL14705953 | 0.75 | ESR1 (0.46) | ESR1ESR2IKBKBCDC7KDM4E | |
| SCHEMBL9047369 | 0.75 | ESR1 (0.46) | ESR1ESR2KDM4EHPGD | |
| SCHEMBL14705951 | 0.74 | PIN1 (0.60) | ESR1ESR2PARP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712847-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL DRUG | NIPPON SODA CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |