Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934352 | 0.81 | TYR (0.41) | APPTYRGAADAO | |
| SCHEMBL10892930 | 0.81 | APP (0.40) | APPTYRGAADAO | |
| SCHEMBL13422405 | 0.79 | DAO (0.45) | APPTYRGAADAO | |
| SCHEMBL4140429 | 0.79 | TYR (0.39) | APPTYRGAADAO | |
| SCHEMBL9012918 | 0.75 | APP (0.41) | APPTYRGAADAO | |
| SCHEMBL9012854 | 0.72 | HTR2A (0.42) | APPADRA1A | |
| SCHEMBL14478190 | 0.72 | APP (0.34) | APPTYRGAADAOADRA1A | |
| SCHEMBL1584769 | 0.72 | DAO (0.53) | APPTYRDAO | |
| SCHEMBL16231972 | 0.72 | APP (0.37) | APPTYRDAO | |
| SCHEMBL10895825 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435333-B1 | Cephalosporin derivatives, the process for preparing the same, and antimicrobial composition containing the derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5262411-A | Isocephem derivatives, and antimicrobial composition containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0435333-A2 | Cephalosporin derivatives, the process for preparing the same, and antimicrobial composition containing the derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |