SCHEMBL7934352

SCHEMBL7934352

O=c1cc(CO)[nH]cc1O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.41
DAO P14920 2/20 0.41
KDM4E B2RXH2 1/20 0.41
PDPK1 O15530 1/20 0.40
APP P05067 5/20 0.40
GAA P10253 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4140429 0.98 TYR (0.39) TYRDAOKDM4EPDPK1APP
SCHEMBL10892930 0.83 APP (0.40) TYRDAOKDM4EAPPGAA
SCHEMBL9049550 0.81 APP (0.39) TYRDAOAPPGAA
SCHEMBL13422405 0.81 DAO (0.45) TYRDAOAPPGAAHCAR2
SCHEMBL3326691 0.77 PDPK1 (0.39) DAOPDPK1
SCHEMBL9012918 0.76 APP (0.41) TYRDAOKDM4EAPPGAA
SCHEMBL9012854 0.74 HTR2A (0.42) APP
SCHEMBL1584769 0.74 DAO (0.53) TYRDAOAPPHCAR2
SCHEMBL16231972 0.74 APP (0.37) TYRDAOKDM4EAPP
SCHEMBL14478190 0.74 APP (0.34) TYRDAOKDM4EAPPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962480-A CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US claimed
US-20250186381-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT DANESH ANDRE (US) 2025-06-12 US disclosed
US-20250064771-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT DANESH ANDRE (US) 2025-02-27 US disclosed
US-20250064942-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT DANESH ANDRE (US) 2025-02-27 US disclosed
US-20240343679-A1 Artificial oxygen carrier blood product DANESH ANDRE (US) 2024-10-17 US disclosed
EP-2906216-B1 INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS KUMAR AJAY (GB) 2020-06-24 EP disclosed
US-9643979-B2 Inhibitors of DNA gyrase for the treatment of bacterial infections VITAS PHARMA RESEARCH PRIVATE LIMITED (IN) 2017-05-09 US disclosed
CN-104529885-B Has multiple bioactive pyridone ketone derivatives and application thereof 浙江工商大学 2016-06-22 CN disclosed
US-20150284408-A1 INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS KUMAR, AJAY, DR. (GB) 2015-10-08 US disclosed
EP-2906216-A2 INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS Vitas Pharma Research Private Limited (IN) 2015-08-19 EP disclosed
US-20090198063-A1 NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-08-06 US disclosed
US-20090198063-A1 NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-08-06 US disclosed
EP-2022793-A1 NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-02-11 EP disclosed
US-6232340-B1 HYDROXYOXOVANADIUM, MU-OXO DIMERIC OXOVANADIUM AND CIS-DIOXOVANADIUM COMPLEXES, ARE ANTI-PROLIFERATIVE AND/OR ANTI-METASTATIC AGENTS TO TREAT DIABETES, ARTHRITIS, MULTIPLE SCLEROSIS, PSORIASIS AND LUPUS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2001-05-15 US disclosed
EP-0984971-A1 VANADIUM COMPLEXES AND DERIVATIVES THEREOF AND METHODS RELATED THERETO Angiotech Pharmaceuticals, Inc. (CA) 2000-03-15 EP disclosed
US-5962480-A CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
WO-1998049173-A1 VANADIUM COMPLEXES AND DERIVATIVES THEREOF AND METHODS RELATED THERETO ANGIOTECH PHARMACEUTICALS, INC. (CA) 1998-11-05 WO disclosed
EP-0838220-A1 DRUG FOR AMELIORATING BRAIN DISEASES WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0594585-A1 IRON ASSAY BRITISH TECHNOLOGY GROUP LTD (GB) 1994-05-04 EP disclosed
WO-1991011720-A1 IRON ASSAY BRITISH TECHNOLOGY GROUP LTD (GB) 1991-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343679-A1 Artificial oxygen carrier blood product TFRC, HBB, HBG2 TYR 503/4885DAO 98/4885KDM4E 2415/4885
US-20250186381-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT TFRC, FTH1, HBB TYR 304/4885DAO 39/4885KDM4E 3898/4885
US-20250064771-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT HBB, HBG2, TFRC TYR 257/4885DAO 34/4885KDM4E 3900/4885
US-20150284408-A1 INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS TOP1, TOP2A, DNASE1 TYR 4216/4885DAO 1110/4885KDM4E 2901/4885
US-20250064942-A1 ARTIFICIAL OXYGEN CARRIER BLOOD PRODUCT HBB, HBG2, TFRC TYR 240/4885DAO 36/4885KDM4E 3919/4885
US-20090198063-A1 NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF IKZF3, ZC3HAV1L, H1-4 TYR 179/4885DAO 658/4885KDM4E 1732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.