Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9049560

CCCC(=O)ON.O=C(O)C(F)(F)F

nearest known ligand 0.44

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
FAAH O00519 8/20 0.38
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
CES1 P23141 6/20 0.36
CES2 O00748 4/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
S1PR1 P21453 4/20 0.33
S1PR3 Q99500 4/20 0.33
S1PR2 O95136 3/20 0.33
S1PR5 Q9H228 3/20 0.33
DPP4 P27487 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24219 0.84
Phosphine SCHEMBL28807315 0.82
SCHEMBL27956729 0.82
Hydrochloric Acid SCHEMBL7592411 0.82
Trifluoroacetic Acid SCHEMBL27503815 0.81 TSHR (0.50) ALDH1A1FAAHFFAR3HDAC3HDAC1
Oxalic Acid SCHEMBL28297998 0.80 ALDH1A1 (0.50) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Trifluoroacetic Acid SCHEMBL27351402 0.79 CYP1A2 (0.45) ALDH1A1FAAHFFAR3HDAC3HDAC1
Trifluoroacetic Acid SCHEMBL28778382 0.78 ALDH1A1 (0.43) ALDH1A1FAAHFFAR3HDAC3HDAC1
Trifluoroacetic Acid SCHEMBL28207918 0.77 ALDH1A1 (0.39) ALDH1A1FAAHFFAR3HDAC3HDAC1
Trifluoroacetic Acid SCHEMBL5069426 0.76 FFAR3 (0.42) ALDH1A1FAAHFFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0715623-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-06-12 EP disclosed