Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048914 | 0.89 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9045791 | 0.86 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9049483 | 0.85 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9046540 | 0.84 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9074195 | 0.84 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9049108 | 0.83 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9047280 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9073667 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9074664 | 0.82 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9048169 | 0.82 | ALOX5 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |