Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | CD74 | P04233 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051648 | 0.84 | PREP (0.60) | ALDH1A1RAB9ANPC1SMN1; SMN2PREP | |
| SCHEMBL9048816 | 0.84 | POLB (0.46) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9049063 | 0.83 | PREP (0.52) | L3MBTL1RAB9ANPC1PREPHRH3 | |
| SCHEMBL9049484 | 0.82 | PREP (0.48) | RAB9ANPC1PREPHRH3 | |
| SCHEMBL9046320 | 0.81 | PREP (0.47) | PREPHRH3 | |
| SCHEMBL5092539 | 0.79 | MAPT (0.59) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9169299 | 0.75 | MAPT (0.44) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9046667 | 0.74 | RAB9A (0.36) | MAPTPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9045731 | 0.74 | PREP (0.39) | ALDH1A1SMN1; SMN2PREPTSHR | |
| SCHEMBL9049902 | 0.72 | F2 (0.48) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |