Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048588 | 0.94 | PTGIR (0.54) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9048942 | 0.89 | PTGIR (0.55) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9427130 | 0.84 | PTGIR (0.52) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9048523 | 0.82 | PTGIR (0.50) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9046455 | 0.82 | TBXAS1 (0.51) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9050354 | 0.82 | PTGIR (0.57) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9427223 | 0.82 | PTGIR (0.53) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9050662 | 0.81 | PTGIR (0.47) | PTGIRPTGDR2TBXAS1 | |
| SCHEMBL9050478 | 0.80 | PTGIR (0.39) | PTGIR | |
| SCHEMBL9050054 | 0.79 | PTGIR (0.55) | PTGIRPTGDR2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |