Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 4/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684290 | 0.92 | MEN1 (0.53) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10680718 | 0.89 | POLB (0.54) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9048301 | 0.89 | KCNH2 (0.53) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8554756 | 0.85 | MEN1 (0.61) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL8116711 | 0.84 | POLB (0.49) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9047018 | 0.84 | TOP2A (0.42) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10377463 | 0.83 | TOP2A (0.40) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9677389 | 0.82 | KCNH2 (0.53) | MEN1KMT2AKCNH2POLBTOP2A | |
| SCHEMBL9049511 | 0.82 | KCNH2 (0.59) | KCNH2POLBTOP2ATOP2BKDM4E | |
| SCHEMBL10679869 | 0.82 | MEN1 (0.53) | MEN1KMT2AKCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287951-B1 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | claimed |