⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050227 | 1.00 | — | — | |
| SCHEMBL2012202 | 0.91 | — | — | |
| SCHEMBL2004903 | 0.83 | — | — | |
| SCHEMBL2505938 | 0.83 | — | — | |
| SCHEMBL9047759 | 0.83 | — | — | |
| SCHEMBL2012215 | 0.77 | — | — | |
| SCHEMBL2008478 | 0.71 | — | — | |
| SCHEMBL7421159 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL9640691 | 0.67 | — | — | |
| SCHEMBL726263 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |