Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PARG | Q86W56 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047400 | 0.90 | GAA (0.54) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL9049151 | 0.83 | MEN1 (0.46) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL11270422 | 0.83 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL10487932 | 0.83 | MAPT (0.61) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL9057858 | 0.82 | POLB (0.57) | LMNASMN1; SMN2TSHRPOLBMEN1 | |
| SCHEMBL11262526 | 0.81 | LMNA (0.73) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL9048107 | 0.80 | GAA (0.53) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL9049590 | 0.79 | LMNA (0.61) | LMNASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL9050328 | 0.79 | TSHR (0.51) | SMN1; SMN2MAPTTSHRPOLBMEN1 | |
| SCHEMBL10048213 | 0.79 | POLB (0.53) | LMNASMN1; SMN2MAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |